1. High BP at Night, Alzheimer's Risk May Rise, Too

    High BP at Night, Alzheimer's Risk May Rise, Too

    Older men whose blood pressure rises at night may be at increased risk for Alzheimer's disease, a new study suggests.

    Blood pressure changes over 24 hours. It typically goes up during the day and dips at nighttime. But some people have an opposite pattern, which is called reverse dipping.

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  5. Quotes

    1. The night is a critical period for brain health. For example, in animals, it has previously been shown that the brain clears out waste products during sleep, and that this clearance is compromised by abnormal blood pressure patterns.
    2. Since the night also represents a critical time window for human brain health, we examined whether too high blood pressure at night, as seen in reverse dipping, is associated with a higher dementia risk in older men.
    3. The risk of getting a dementia diagnosis was 1.64 times higher among men with reverse dipping compared to those with normal dipping. Reverse dipping mainly increased the risk of Alzheimer's disease, the most common form of dementia.
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